Key points about staphylococcal scalded skin syndrome in children. Eventually, exfoliation occurs. Treatment of staphylococcal scalded skin syndrome Girish K Patel Humans are a natural reservoir for Staphylococcal aureus. Scalded skin syndrome: A potentially serious side effect of infection with the Staph (Staphylococcus) bacteria that produces a specific protein which loosens the “cement” holding the various layers of the skin together.This allows blister formation and sloughing of the top layer of skin. Staphylococcal scalded skin syndrome (Fig. Urata T, Kono M, Ishihara Y, Akiyama M Acta Derm Venereol 2018 Jan 12;98(1):136-137. doi: 10.2340/00015555-2770. Adult Staphylococcal Scalded Skin Syndrome Successfully Treated with Multimodal Therapy Including Intravenous Immunoglobulin. Background. J Paediatr Child Health. (Discusses the use of intravenous immunoglobulin in the treatment of a pre-term infant with SSSS.) The disease can be life-threatening and needs treatment. 2004 Aug2(4):575-87. To guide PCH ED staff with the assessment and management of staphylococcal scalded skin syndrome in children. Johnston GA; Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in Expert Rev Anti Infect Ther. Staphylococcal scalded skin syndrome is caused predominantly by phage group 2 staphylococci, particularly strains 71 and 55, which are present at localized sites of infection. INTRODUCTION. Staphylococcal scalded skin syndrome is the serious life-threatening disease which response to a toxin produced by a Staphylococcal aureus infection. Foci of infection include the nasopharynx and, less commonly, the umbilicus, urinary tract, a superficial abrasion, conjunctivae, and blood. Skin care (the skin is often very fragile). administered in the treatment of staphlococcal scalded skin syndrome; modalities nafcillin or oxacillin in methicillin-sesitive Staphylococcus aureus (MSSA) vancomycin in cases of methicillin-resistant Staphylococcus aureus (MRSA) Complications Monitoring and maintaining fluid and electrolyte intake. Staphylococcal scalded skin syndrome is a bacterial infection. SSSS is a highly contagious disease and is characterised by erythema and fever, followed by the formation of large … Staphylococcal Scalded Skin Syndrome, also known as Ritter disease is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. In children, the disease usually starts with fussiness, tiredness, and a fever. Use of skin substitute dressings in the treatment of staphylococcal scalded skin syndrome in neonates and young infants. Staphylococcal scalded skin syndrome (SSSS) is an exfoliative toxin-mediated dermatitis that predominantly occurs in young children. Treatment is antistaphylococcal antibiotics and local care. Treatment for Staphylococcal Scalded Skin Syndrome. Staphylococcal scalded skin syndrome (SSSS) is an acute dermatological illness which requires prompt treatment. Staphylococcal scalded skin syndrome (SSSS) is the clinical term used to describe a range of blistering skin disorders induced by the exfoliative toxins of Staphylococcus aureus and prevalently affects neonates, infants and toddlers who lack antibodies to S. aureus toxins. SSSS is most common in infants and children, but can also affect adults with a depressed immune system or problems with kidney function. Colonization begins soon after birth and predisposes to infection. SSSS is treated with the following: Antibiotic Treatment. A skin infection characterized by damaged, shedding skin patches, staphylococcal scalded skin syndrome is a progressive disorder. Other supportive treatments for staphylococcal scalded skin syndrome include: Acetaminophen (paracetamol) when necessary for fever and pain. Staphylococcal Scalded Skin Syndrome is a pathological condition usually found in children and immune compromised individuals caused due to bacteria Staphylococcus aureus. Antibiotic treatment is usually given intravenously. BACKGROUND: Staphylococcal scalded skin syndrome (SSSS) is a rare toxin-mediated skin disease caused by Staphylococcus aureus and seen in infants and children younger than 5 years. This condition is characterized by blistering in the skin surface which more or less looks like a burn and that is what gives it the name of Staphylococcal Scalded Skin Syndrome. Tenenbaum T, Hoehn T, Hadzik B, et al. Staphylococcal scalded skin syndrome (SSSS) is a potentially serious acute skin condition caused by the exfoliative toxins of Staphylococcus aureus and typically affects infants and young children. The toxins elaborated by these the exfoliative toxins A and B causes the SSSS. Caused by a toxin emitted by the bacterium, rather than actual bacterial components, this syndrome leads to broad regions of exfoliating skin and is mainly observed in immunocompromised patients, newborns, infants and young children. indications. Diagnosis is by examination and sometimes biopsy. Staphylococcal scalded skin syndrome (SSSS) is a response to a Staphylococcus “staph” infection. The primary goal of treatment for SSSS is to eradicate the causative agent. Staphylococcal scalded skin syndrome (SSSS) is a rare disorder with clinical features varying from superficial localized blisters to generalized exfoliation. Successful results are achieved in this case due to timely and correct management. Symptoms are widespread bullae with epidermal sloughing. Staphylococcal scalded skin syndrome (SSSS) is counted as one of the major skin infections. 2011. Caused by the Staphylococcus bacteria, the condition is the result of poison produced by the bacteria that damages the skin. 44. In this infection, skin surface of large parts of body gets peeled off and looks like burned skin by hot liquid . It is characterized by the sudden onset of fever, skin tenderness, and erythema, followed by the formation of large, flaccid bullae and shedding of large sheets of skin, leaving a denuded, scalded-appearing surface. Kapoor, V, Travadi, J, Braye, S. “Staphylococcal scalded skin syndrome in an extremely premature neonate: a case report with a brief review of literature”. 1-4 Recommended treatment for SSSS includes antistaphylococcal antibiotics and supportive care measures. Multiple recent reports indicate a rising incidence of this disease. The disease can be life-threatening and needs treatment. vol. Staphylococcal scalded skin syndrome is usually from a bacterial infection. the skin causing it blister and to peel. Staphylococcal scalded skin syndrome (SSSS) is a dermatological condition caused by Staphylococcus aureus Signs and symptoms. They called this disease entity staphylococcal scalded skin syndrome (SSSS). It causes a reddening and blistering of the skin that gives it a scalded or burned look. 374-6. Aim. Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins (also known as epidermolytic toxins, epidermolysins and exfoliatins) of Staphylococcus aureus [1, 2].Its severity varies from localized blisters to generalized exfoliation affecting the entire body surface []. The disease mostly affects infants, young children, and individuals with a depressed immune system or renal insufficiency. and reproduced the skin lesions using cultured supernatant strain TA (phage type 71, Group 2) in a neonatal mouse model. 10.1B) is an uncommon disorder affecting primarily infants and young children. The clinical term SSSS is used to describe a range of blistering skin disorders induced by the exfoliative toxins (ETs) of Staphylococcus aureus.ETsare 100 (1):9-13. . This is followed by redness of the skin. Eur J Pediatr. Some therapeutic options are widely used without thorough research bases. This condition generally affects children < 5 years of age, and can be a severe and potentially life threatening illness, particularly in neonates Staphylococcal scalded skin syndrome is an acute epidermolysis caused by a staphylococcal toxin. This is followed by redness of the skin. Staphylococcal scalded skin syndrome (SSSS), also known as Ritter disease and staphylococcal epidermal necrolysis, is a toxin-mediated condition caused by Staphylococcus aureus.The exfoliative toxin produced disseminates and cleaves desmoglein 1 in the epidermis, causing separation and detachment of the skin. SSSS is also called as Ritter von Ritterschein disease, Ritter disease, Lyell disease and staphylococcal necrolysis of epidermis. In children, the disease usually begins with fussiness (irritability), tiredness (malaise), and a fever. OBJECTIVES: The supportive role of skin substitutes in SSSS is stressed as a new and relatively unknown method. The main route of This disease leads to peeling of outer layer skin to blister or it looks like burned by hot liquid. Neonatology. It is more common in infants than adults. Staphylococcal scalded skin syndrome (SSSS) is a potentially lethal complication of a Staphylococcus aureus infection. Key points about staphylococcal scalded skin syndrome in children. This case report highlights staphylococcal scalded skin syndrome and its treatment, and future challenges. When the bacterium is eradicated, the toxin causing damage to the skin cells will also be eradicated. Liter produces these exfoliative toxins. It is important to swab the skin for bacteriological confirmation and antibiotic sensitivities and, in the case of staphylococcal scalded skin syndrome, to identify the primary focus of infection. Staphylococcal scalded skin syndrome, which is caused by several toxins termed exfoliatins, is an exfoliative dermatitis of childhood characterized by large bullae and peeling of the upper layer of skin. Expert Rev Anti Infect Ther. Exchange transfusion in a preterm infant with hyperbilirubinemia, staphylococcal scalded skin syndrome (SSSS) and sepsis. 2004 Jun2(3):439-46. Currently, the incidence of this disease is increasing in all ages. Infants and children are most susceptible. The affected skin initially looks red, resembling a scald or burnand is very tender to touch which is why the, condition is called the staphylococcal scalded skin syndrome. 5,6 Elimination or reduction of the toxin-producing Staphylococcus aureus is thought … Patel GK; Treatment of staphylococcal scalded skin syndrome. It usually presents 48 hours after birth and is … The mainstay of treatment for SSSS is supportive care along with eradication of the primary infection. Staphylococcal Scalded Skin Syndrome (SSSS) or acute staphylococcal epidermolysis is an exfoliative skin disease and a toxin mediated staphylococcal infections affecting mostly neonates and adolescents and it is rare in adults [1, 2]. It is a condit Staphylococcus aureus (SA). Scalded skin syndrome most commonly occurs in infants and children < … The latest treatment options are used and described. S. aureus, mediated by toxin production, also can cause toxic shock syndrome and staphylococcal scalded skin syndrome. Treatment: Medical intravenous anti-staphylococcal antibiotics. Jul 2007. Staphylococcal scalded skin syndrome is a response to a toxin produced by a staphylococcal infection and is characterized by peeling skin. What causes the staphylococcal scalded skin syndrome? 2008. pp. Treatment.